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Search Results for " tissue plasminogen activator "

Targets

15

Compounds

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T3359 Aprotinin Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin Others , Serine Protease , Influenza Virus , Proteasome
Aprotinin (Traskolan) a broad-spectrum serine protease inhibitor, inhibiting the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activat...
T69890 PS-519
PS-519 is a human tissue plasminogen activator and proteasome inhibitor.
T70734 U46,195
U46,195 stimulates the production of tissue-type plasminogen activator, and is a PAF antagonist.
T69319 U 34599
U 34599 stimulates the production of tissue-type plasminogen activator.
T68659 Valyl-glycyl-arginine-4-nitroanilide
Valyl-glycyl-arginine-4-nitroanilide is a tissue plasminogen activator.
T71851 5-trans-Prostaglandin E2
5-trans-Prostaglandin E2 accelerates fibrinolysis by enhancing plasminogen activation mediated by tissue-type plasminogen activator. It also inhibits platelet aggregation in human PRP.
T41085 UK122 UK122
UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA),...
T70810 THR-18
THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncoup...
T40614 LCKLSL
LCKLSL, an N-terminal hexapeptide, acts as a competitive inhibitor of annexin A2 (AnxA2), effectively preventing the binding of tissue plasminogen activator (tPA) to AnxA2 while also inhibiting the generation of plasmin....
T11152 Edaravone-d5 MCI-186 D5 Others
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the origin...
T68513 BSc2118
BSc2118 is a potent proteasome inhibitor. BSc2118 shows significant antimyeloma activity and may be considered as a promising agent in cancer drug development. BSc2118 is also a promising new candidate for stroke therapy...
T78018 Plasminogen
Plasminogen is a zymogen secreted as a precursor protein that, when cleaved by urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA), is converted into plasmin. Plasmin is a protease with broad spec...
T64287 Reteplase
Reteplase (BM 06.022) is a recombinant plasminogen activator consisting of the kringle 2 and protease domains of human tissue-type fibrinogen activator. Reteplase is produced by DNA technology in E. coli as a t-PA mutant...
TP2482 LCKLSL acetate LCKLSL acetate(533902-29-3 free base) Annexin A
LCKLSL acetate is a competitive annexin A2 (AnxA2) inhibitor. LCKLSL acetate potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2 and the generation of plasmin. LCKLSL acetate has anti-angiogenic ...
T78015 LCKLSL hydrochloride
LCKLSL hydrochloride, an N-terminal hexapeptide and competitive annexin A2 (AnxA2) inhibitor, effectively disrupts the interaction between tissue plasminogen activator (tPA) and AnxA2. It additionally hinders plasmin gen...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00332 TPA Protein, Human, Recombinant (His) Human HEK293 Cells
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs...
TMPY-00938 TPA Protein, Human, Recombinant Human HEK293 Cells
tPA Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 28 kDa and the accession number is P00750-1.
TMPY-00937 TPA Protein, Human, Recombinant (hFc) Human HEK293 Cells
tPA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.5 kDa and the accession number is P00750-1.
TMPY-02898 TPA Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
tPA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.4 kDa and the accession number is P11214.
TMPK-00810 TPA Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin...
TMPJ-00625 Serpin E1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. I...
TMPJ-00501 CLEC3B Protein, Human, Recombinant (His) Human HEK293 Cells
C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind...
TMPH-02832 Serpin A5 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extr...
TMPH-02834 PAI-1 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-reg...
TMPJ-00490 Serpin A5 Protein, Human, Recombinant (His) Human HEK293 Cells
Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent i...
TargetMol